Tante Girang Genit Asia Physiology of fluid resuscitation Thermal injuryto the the skin manifest as coagulation necrosis with microvascular thrombosis in areas that most of the damage . Surrounding tissue usually had burns that are not too severe, with stasis and hiperemia that its boundaries are not clear. Areas that potentially could be saved, earned perfusion of microcirculation damage. If patients with extensive burns do not immediately get the proper fluid resuscitation, then
shock may occur due to burns and cuts part of the injury but will still alive, and will continue to be necrosis. Quinine, prostanoid, histamine, and oxygen radicals appear to play an important role in determining the severity of tissue injury. Ibuprofen can save the skin blood vessels and reduce edema arising early after burns. Fluid resuscitation is to strengthen the formation of edema in the tissue, both suffered burns or not. Edema is not will always be bad, if recovered will not leave permanent damage. The liquid that comes out and the room is very similar intravascular plasma, both in terms of protein content and the electrolyte. Baxter and Shire have shown that loss of sodium is approximately 0.5 to 0.6 meq / kg body weight /% body surface burned. Acute hemolysis caused by direct damage to cells red blood due to heat. Activation of complement due to burns and subsequent production of oxygen radicals by neutrophils increased osmotic fragility of red blood cells, and cause hemolysis lasted for several days after thermal injury. In the first 24 hours after injury, hematocrit values as high as 70% relatively often found in a previously healthy young people.